体形指数增加的男性易发生不育

美国国立环境健康科学深入研究组进行的一项深入研究断定，与正常人肥胖的女性相对于，肥胖加权增高的女性子代可能性非常大。

Markku Sallmen就职于芬兰职业健康深入研究组。他真是：“数据库揭示，女性肥胖每增高20磅（大约9公斤），子代的可能性将增高10%。”肥胖加权是由人的肥胖和身较高近似值以此的数据库，对大多数人，肥胖加权可成为全身成年人的可靠指标，也常被用来筛查肥胖增重。

学者对农业健康深入研究计划案当中注册的前夫进行了深入研究。这项始于1993年的计划案目的是为了检测不良影响农业社区农民及其妻儿生活品质的状况。

国立环境健康科学深入研究组的统计学家Donna Baird博士真是：“与肥胖正常人的妇女相对于，增重或成年人的妇女较难怀孕，但是比方说情况的女性否存有分娩问题未曾有人深入研究。”这项结果发表在2006年9月初《统计学杂志》上。

子代和肥胖加权的资料叫作1468位农民和他们的母亲在登记归入这项深入研究时完成的问卷调查。后者完成妻儿生活品质调查表，包含前夫的分娩巨著，前者报告妻儿肥胖和身较高的调查表。深入研究分析受限制注册4年前决意分娩及女方年纪略低于40的前夫。

学者将这些前夫分为子代组和可育组，至多于1年未不孕者归为子代组，在1年内不孕者归为可孕组。大多数女性和女性年纪至多于30岁，28%的前夫有子代症状。

学者断定女性的肥胖加权是子代症的法理致命状况。深入研究员调整了其它不良影响分娩力的状况，如女性的较高肥胖加权、年纪、吸烟、饮酒、暴露于杀虫剂，调整进行时，随着肥胖加权的增高，子代呈线性增高，在成年人女性，子代赴援增高1倍。学者还断定无论年纪尺寸，女性的肥胖加权都是子代症的致命状况。

虽然不会阈值的数据库，但据推测增重的女性较肥胖正常人的女性次数多于，从而不良影响了分娩。然而，关于精子结构上的深入研究断定增重和成年人的女性，精子质量低，激素不抵消。

国立环境健康科学深入研究组的主任Did A. Schwartz博士真是：“这项深入研究提出了某些与成年人有关的另外的生活品质问题，抑制成年人可作出贡献女性性生活，其当中就包含他们的生殖生活品质。”该深入研究组还提出了一项最初集当中力量的计划案——“环境科学和本能生活品质的新前沿”，这项计划案将于明年5月初实施，目的在于利用环境健康科学作出贡献社会公众认识哮喘的胃癌原因并作出贡献本能生活品质。

Men with increased body mass index (BMI) were significantly more likely to be infertile than normal-weight men, according to research conducted at the National Institute of Environmental Health Sciences (NIEHS), one of the National Institutes of Health."The data suggest that a 20-pound increase in men's weight may increase the chance of infertility by about 10 percent," says Markku Sallmen, lead author on the paper who is now at the Finnish Institute of Occupational Health. BMI is a number calculated from a person's weight and height. BMI provides a reliable indicator of body fatness for most people and is used to screen for weight categories that may lead to health problems.The researchers studied couples enrolled in the Agricultural Health Study (AHS), a large project that began in 1993 examining factors that impact the health of farmers and their families in agricultural communities. "Women who are overweight or obese tend to he a more difficult time becoming pregnant than normal-weight women, but whether men who are overweight or obese also he fertility problems had not been studied," says Donna Baird, Ph.D., an NIEHS epidemiologist with the study. The study is published in the September 2006 issue of Epidemiology.The data on infertility and body mass came from questionnaires that 1,468 farmers and their wives completed when they enrolled in the study. The wives completed a family health questionnaire, which included information about the couple's reproductive history. The men reported their weight and height on a questionnaire about their health. The ysis was limited to couples with a pregnancy attempt during the four years before enrollment, and to women under the age of 40. The researchers divided the couples into infertile and fertile groups. The infertile couples were those that tried for longer than a year to conceive, and the fertile couples were those that conceived within a year. The majority of men and women were more than 30 years old. Twenty-eight percent of the couples had experienced infertility.Researchers found that men's BMI was an independent risk factor for infertility. The researchers adjusted for other factors that could affect fertility, including high BMI of the woman, age, cigarette smoking, alcohol intake, and solvent and pesticide exposure. After adjustment, there was a general increase in infertility with increased BMI, reaching a nearly 2-fold increase among obese men. When researchers divided the sample into two equal groups by men's age, they found that men's BMI was a risk factor for infertility in both the older and younger men.The researchers did not he data on frequency of sexual intercourse, so it is possible that overweight men he less sexual intercourse than their normal weight counterparts and this could influence fertility. However, there he been recent studies looking at semen characteristics that show lower semen quality for overweight and obese men, as well as hormonal differences."This study provides data on some additional health problems associated with obesity," said Did A. Schwartz, M.D., director of the National Institute of Environmental Health Sciences. "Preventing obesity can help improve men's overall health, perhaps even their reproductive health."The NIEHS unveiled a new strategic plan, "New Frontiers in Environmental Sciences and Human Health," in May aimed at challenging and energizing the scientific community to use environmental health sciences to understand the causes of disease and to improve human health.叫作

撰稿人：橙色幻想

撰稿人： 张靖